When talking about male infertility, the most common causes are usually taken into account. However, some alterations are often associated with other diseases and underlying conditions that can lead to the development of further complications, which, if detected early, are feasible to correct or lead to more effective alternative solutions.
Oligospermy is one of the prevalent and consequential conditions that can impede conception in males. It is characterized by a reduced sperm count in the semen. According to data from the World Health Organization (WHO), a man is considered to have oligospermy if his sperm concentration is less than 15 million spermatozoa per milliliter.
Oligospermy can be caused by various diseases, such as hormonal disorders, testicular problems or infections. In many cases, Oligospermy is associated with other conditions, such as those described below:
Cryptorchidism: a condition associated with oligospermy
Cryptorchidism is a condition characterized by the failure of one or both testicles to descend into the scrotum before birth. This condition can lead to fertility challenges since the undescended testicles are exposed to higher temperatures, which can adversely affect sperm production.
Cryptorchidism predominantly affects a single testicle in about 80% of cases, with the left testicle being the most commonly affected. Bilateral cryptorchidism, where both testicles are undescended, is less frequent. To mitigate the risk of fertility difficulties, boys diagnosed with cryptorchidism should undergo surgical intervention to bring down the testicles into the scrotum before the age of 2 years.
Varicocele
Testicular varicocele is a condition that causes dilation of the veins supplying the testicles. This can cause an elevation of testicular temperature, which can impact sperm production. It is most common in one testicle, but can also influence both. If it influences both testicles, it is more likely to cause infertility.
Additionally, testicular varicocele can lead to a condition called oligoasthenoteratozoospermia, which is characterized by low-quality spermatozoa in terms of both quantity and quality, including motility and morphology.
It can certainly improve if properly treated, and surgery is usually the most effective treatment, especially in severe cases.
Hypogonadism and oligospermy: links in reproductive health
Male hypogonadism is a condition in which the testicles do not produce enough sex hormones, such as testosterone. This affects sperm production and can cause infertility as well.
Male hypogonadism can be classified into two main types:
- In cases of primary hypogonadism, the testes experience dysfunction caused by internal problems. Klinefelter’s syndrome, one of the most prevalent genetic disorders within this category, can lead to reduced testosterone levels, decreased muscle mass, inadequate development of facial and body hair, and diminished sperm production.
- In cases of secondary hypogonadism, the issue lies in the hypothalamus or pituitary glands, which are responsible for producing the hormones that stimulate the testes to produce sperm.
The treatment of hypogonadism is determined by the specific type of the condition. Hormonal therapy can be utilized in certain cases to restore testicular function and stimulate increased sperm production, ultimately improving the outlook for fertility.
Hydrocele
Testicular hydrocele is a condition that causes fluid to accumulate around one or both testicles. It can be congenital or acquired, and is more common in men over 40 years of age.
Hydrocele is generally not a direct cause of infertility, although it may be associated with infertility in around 10% of cases. In these instances, it can lead to a partial obstruction of the vas deferens, potentially resulting in a decreased sperm count in the semen.
Oligoasthenoteratozoospermia
Oligotherotherozoospermia is a condition in which the concentration of spermatozoa in the semen is low and the shape of the spermatozoa is abnormal. This term brings together two spermogram findings, “Oligo” which refers to a low sperm concentration (less than 15 million x ML), and “terato” refers to a low concentration of normal shaped sperm (less than 4%). Abnormalities in sperm shape hinder fertilization and may also affect embryo development.
For men with severe oligoteratozoospermia who desire to conceive, in vitro fertilization (IVF) treatment with intracytoplasmic sperm injection (ICSI) is typically recommended. This procedure involves the selection of sperm with good morphology under a microscope, which are then directly injected into the egg. This technique enhances the likelihood of developing a healthy embryo.
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Although these diagnoses may dampen the hopes of men who aspire to have a family, it is essential to understand the positive significance of detecting and addressing these conditions on time. This realization can mark a transformative phase in enhancing fertility and promoting overall health.
It is advisable to keep up to date with general check-ups, not only to increase the chances of being able to start a family, but also to avoid these diagnoses that can lead to irreversible consequences. These diagnoses can compromise the health and well-being of patients.
If you are aspiring to start a family but are encountering difficulties in conception or are aware of someone facing infertility or related complications, it is essential to reach out to specialized clinics that specialize in oligospermy, male fertility, and assisted reproduction, such as Babynova Clinic by Novafem. Seeking advice and treatment from these clinics at the earliest opportunity can make a significant difference in addressing these issues.



